RWE
Real-world evidence.
Evidence derived from real-world data — registries, claims, EHRs, chart reviews — used to complement RCTs in HTA, label expansion and post-marketing commitments.
Real-world evidence (RWE) is clinical evidence about the usage and benefits or risks of a medical product derived from analysis of real-world data — registries, claims, electronic health records, chart reviews. HTA bodies are increasingly willing to accept RWE, but the bar on bias control, fit-for-purpose data and pre-specification is higher than for RCTs.
A markdown template covering PICO, eligibility, effect modifiers, choice of method, sensitivity analyses and reporting — drop into your study folder.
Structured search across PubMed, Embase, congress abstracts and HTA decisions, deduplicated and screened with reviewer-grade criteria.
Scaffold anchored and unanchored MAICs, NMAs and standard ITCs — assumptions tracked, sensitivity pre-run, code your ERG or IQWiG can reproduce.