NICE submission
A company evidence submission your ERG won't tear apart.
Knowledgeable builds your NICE company evidence submission against the reference case: ITCs pre-checked, model inputs reproducible, and every assumption traceable to the trial, the label or the published evidence base.
Watch it run on your work.
Where this fits in your workflow.
Knowledgeable builds your NICE company evidence submission against the reference case: ITCs pre-checked, model inputs reproducible, and every assumption traceable to the trial, the label or the published evidence base.
Most teams running NICE today juggle a stack of search tools, PDF readers and consultancy slides, then spend the back half of the project reconciling claims to sources. Knowledgeable collapses that into one defensible workflow: a company evidence submission your erg won't tear apart.
The work runs against your literature, trial registries, HTA precedent, label and SmPC, with every sentence pinpoint-cited so your senior reviewer opens a document that's already at QC.
- 1Scope & comparator locked
- 2Evidence pulled & graded
- 3Draft built with citations
- 4QC pass against framework
The work that finally lands the way you scoped it.
Reference-case alignment
Structure, perspective and discount rates pre-mapped to the NICE reference case. No rewrites at clarification.
ITCs the ERG can reproduce
MAIC and unanchored ITC scaffolding with assumptions tracked, sensitivity pre-run and code attached.
Pre-built ERG response pack
Anticipated clarification questions drafted before the ERG asks them, grounded in published precedent.
End-to-end traceability
From source publication to model cell to dossier sentence, one chain of evidence your reviewer can follow.
Walk into committee with the answers already drafted.
Book a NICE readiness reviewBuilt for NICE-grade scrutiny.
Reviewer-shaped templates, reproducible analyses and full audit trail. The work survives clarification, committee and appeal.